diabetic nephropathy: pathogenesis and management
نویسندگان
چکیده
abstract
منابع مشابه
Pathogenesis of diabetic nephropathy
As the increasing prevalence of diabetes reaches epidemic proportions worldwide, diabetic nephropathy and associated end-stage renal failure will be an unavoidable major health burden to not only individuals with diabetes and their families, but also to the health systems both in developed and developing countries. Over the past decade, a large body of research has focused on diabetic nephropat...
متن کاملDiabetic Nephropathy: Pathogenesis, Prevention and Treatment
Diabetic Nephropathy (DN) is referred to as the kidney damage that occurs in people with diabetes, the earliest detectable change of which is the thickening in the glomerulus. DN is categorized into two stages; microalbuminuria and macroalbuminuria, in which the kidney leaks more serum albumin than normal in the urine. Increasing numbers of glomeruli are noted to be destroyed by progressive nod...
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The most problematic issue in clinical nephrology is the relentless and progressive increase in patients with ESRD (end-stage renal disease) worldwide. The impact of diabetic nephropathy on the increasing population with CKD (chronic kidney disease) and ESRD is enormous. Three major pathways showing abnormality of intracellular metabolism have been identified in the development of diabetic neph...
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Diabetic nephropathy is the leading cause of end-stage renal failure in developed countries. Furthermore, diabetic nephropathy is related to the risk of cardiovascular diseases and an increase in mortality of diabetic patients. Several factors are involved in the development of nephropathy, including glomerular hyperfiltration, oxidative stress, accumulation of advanced glycation end-products, ...
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1 Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan 2Department of Nephrology, Graduate School of Medicine, Institute of Health Biosciences, University of Tokushima, Tokushima 770-8503, Japan 3Division of Nephrology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee Uni...
متن کاملThe pathogenesis and prevention of diabetic neuropathy and nephropathy.
The chronic complications of diabetes are thought to be caused by an interaction between hyperglycemia, or other metabolic consequences of insulin deficiency, and independent genetic or environmental factors that are poorly defined. Several potentially relevant biochemical sequelae to hyperglycemia have been identified in tissue susceptible to diabetic complications. Among these, a rise in tiss...
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عنوان ژورنال:
journal of kermanshah university of medical sciencesجلد ۲۰، شماره ۳، صفحات ۰-۰
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